Bioassay Scientist
Eurofins

Fremont, California

This job has expired.



Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

Become your most extraordinary self! Our team is intensely proud to be a major provider of services and products to the drug discovery research industry. Join Eurofins DiscoverX Products, LLC part of the Eurofins Discovery ™ group of companies serving global clients in the Pharma and Biotech industries. Work alongside industry experts and collaborate with team members to directly and positively impact human health worldwide!

We have a philosophy to support work life balance, career progression opportunities and offer many benefits such as formal mentoring programs, tuition reimbursement, extensive career training programs, competitive health benefits, paid time off and 10 annual paid holidays*.

Eurofins DiscoverX Products, LLC is a leader in providing innovative solutions to the pharmaceutical industry by developing, manufacturing, and commercializing cell lines, cell-based assay kits, and supporting reagents. The holder of this positionwill be responsible fordevelopment and qualification of bioassays for lot release and neutralizing antibody (NAb) detectionto support catalog expansion as well as client-driven custom projects.

  • Responsible for characterization, manufacture and optimization of custom assay-ready cells to support development of relative potency and NAb assay for client therapeutics using diverse cell-based assay formats.
  • Participates as one of several analysts in Bioassay team who perform assay qualification of custom relative potency assays
  • (bioassays) with client therapeutic agent, generating the required data within timelines defined by client
  • Reviews own assay qualification (or other experimental) results and confirms accuracy before submitting to supervisor / project lead for inclusion in study results / reports
  • Provides appropriate documentation and technical support for downstream users of custom bioassays including generation of SOPs, detailed protocols for user manuals, custom methods, and/ or client reports.
  • Generates detailed cell lot manufacturing / cell passaging and scale-up information to operations team, and trains others to perform assay-ready cell manufacturing as needed
  • Performs new assay development as needed to facilitate rapid development of novel assays for Eurofins DiscoverX product portfolio or custom development projects
  • Presents results in both written and oral format and delivers data and/or reports to appropriate stakeholders within a multidisciplinary team environment in a timely fashion
  • Accurately documents experimental procedures and results in the ELN and stores data on appropriate secure data servers in accordance with company policy

Qualifications

The ideal candidate would possess:
  • Experience developing or running cell-based assays, such as reporter gene assays, cAMP detection, cell proliferation, etc.
  • Experience culturing and freezing engineered cell types such as CHO-K1, HEK, Jurkat or U2OS
  • Prior experience performing relative potency assays strongly preferred
  • Experience with data analysis packages such as SoftMaxPro/PLA module or PLA 3.0 for parallel line analysis strongly preferred
Basic Minimum Qualifications:
  • BS/MS in cell biology, biochemistry, biotechnology or related field with a minimum of 6 years of industry experience.
  • Extensive mammalian cell culture expertise (maintenance and freezing) with HEK, CHO-K1, Jurkat and U2OS, or other comparable cancer cell models
  • Familiarity with various cell-based assay formats (e.g. cAMP, reporter gene assays, etc.), and technology platforms (flow cytometry, immunofluorescence, ELISA)
  • Experience developing and / or running bioassays for relative potency or neutralizing antibody (NAb) detection applications strongly preferred
  • Experience with data analysis packages such as GraphPad Prism, Microsoft Powerpoint and Excel required
  • Ability to work independently, efficiently and productively in a fast-paced, highly collaborative and diverse team environment.

Additional Information
  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.


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