Scientist
Camris International

Overview

CAMRIS is a clinical and life sciences firm that realizes innovative solutions to challenges worldwide through high-quality, cost-effective program and research management services. We combine our proven systems with today's most effective, evidence-based best practices to improve the lives of people around the world. Our core practice areas include HIV/AIDS, microbiology and infectious disease research, vaccine research, development and production, global health security, biodefense, and clinical research.

CAMRIS attracts the next generation of scientists to work at premier government research and development institutions with state-of-the-art facilities and equipment, under world leaders in health research. Our exceptional benefits package that includes medical, dental and vision coverage, 401k plan with employer contribution, paid holidays, vacation, Medical and Flexible Spending Accounts, and life insurance. If you enjoy being a part of a high performing health and research organization dedicated to making the world a healthier place, please apply today!

We are seeking a Scientist to provide services in support of the overall functions of the Vaccine Production Program.

Responsibilities

• Support the Downstream Process Development (purification) group of the Vaccine Production Program (VPP) at the Vaccine Research Center.
• Develop downstream processes for recombinant proteins such as monoclonal antibodies, subunit or nanoparticle vaccines, and virus-like particles (VLPs) that may be used as clinical therapeutic or vaccine candidates.
• Work independently and collaboratively within the purification group to design, develop and optimize chromatography, Tangential Flow Filtration (TFF), and Normal Flow Filtration (NFF) processes for all clinical trial vaccine candidates.
• Apply process optimization techniques, such as Design of Experiments (DoE) or other statistical design approaches.
• Support Viral Clearance Validation studies by traveling to CMO/CRO sites to perform and oversee viral clearance chromatography and filtrations processes.
• Purify research-phase recombinant proteins, virus vaccines and/or virus-like particles in support of other groups at the VRC.
• Analyze and compile data, present at various group/department meetings.
• Pursue novel technologies to advance the capabilities of the VPP.
• Write and review technical reports and method protocols.
• Write and review process batch records for toxicology batch productions.
• Write and review technology transfer documents in support of GMP manufacturing.

Qualifications

• PhD. in a Biochemistry, Chemical Engineering, or other life sciences is required.
• Demonstrated knowledge of maintaining accurate and detailed records.
• Demonstrated proficiency in the following techniques or tools for protein purification and characterization:
  • Column chromatography for protein purification by means of AEX, CEX, affinity, SEC, HIC
  • AKTA chromatography system o Qualitative assays including SDS-PAGE and Western Blot
  • UV/vis spectrophotometer Proficiency in the following is highly desirable, but not required:
  • Column packing and testing o Lab scale TFF systems o Lab scale nano-filtration systems
  • Qualitative assays including SDS-PAGE and Western Blot
  • UV/vis spectrophotometer
• Strong oral and written communication skills.
• Familiarity with computer software including word processing and data evaluation

CAMRIS International LLC offers competitive salaries and comprehensive benefits. Please submit your resume online at www.CAMRIS.com . CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law.

Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.

Full vaccination against COVID-19, defined as two doses of Moderna, two doses of Pfizer, or one dose of Johnson & Johnson's Janssen, is required for this position.

This job has expired.